Roja Ramani was born in Rajahmundry. Her father was 'Cinema Rangam' Satyam. She selected for the title role of 'Bhakta Prahlada' at the age of 5. She done climax scene as her first scene. She got that offer because of AVM Studio's in-charge Nageswara Rao and Rangoon Rama Rao, the co-director of the film. In that movie, S.V. Ranga Rao prtrayed as Hiranya Kasipa. Chitrapu Narayana Murthy was the director.
Dr. Sarvepalli Radhakrishnan, the President of India at that time, was seen 'Bhakta Prahlada' and appreciated the performance of Roja Ramani. He didn't believe when he knew 'Prahlada' was not a boy, but a girl. He given appreciation cerificate to Roja Ramani. She got Best Child Artiste award from State Govt. and took the award on the hands of Kasu Brahmananda Reddy, the Chief Minister of that time. 'Bhakta Prahlada' got Best Regional Film award in National film awards also.
After that film Roja Ramani played good roles in the films like 'Sridevi', 'Sattekalapu Satteiah' and 'Chinnari Papalu' as a child actor.
She did her first film as heroine was in Malayalam. That's 'Chembarathi'. It created sensation in Kerala. She took filmfare award as Best Actress for that film, at the age of just 13 years. It's record of that time. She was the heroine even the Telugu version of the film 'Kanne Vayasu' and Tamil version 'Paruva Kaalam'. The song 'E divilo virisina paarijaatamo' in 'Kanne Vayasu' was so popular even today.
She acted as full pledged heroine in K. Viswanath's film 'O Sita Katha'. That was trendsetter. It got so many awards to Raja Ramani. She gained good name with the films 'Bharatamlo Oka Ammayi', 'Evariki Vaare Yamuna Teere' and 'Balipeetham', the three were directed by Dasari Narayana Rao. She acted as female lead in 50 movies approximately in Telugu, Tamil, Kannada, Malayala, Oriya and Hindi languages. 'Punaadi Raallu' was her 100th film, which was first of Chiranjeevi.
Roja Ramani married Chakrapani in 1981 at the age of 22 years. They both acted together as lead pair in 5 Oriya films, earlier. Theirs was love and arranged marriage.
'Maga Dheerudu', the Chinranjeevi starrer, was the last film of her as an actor. What the spciality of her career was, she acted in 'Tatamma Kala', directed by N.T. Rama Rao, in a tele film 'Kamakshi Katha', directed by Bhanumati and in 'Chinnari Papalu', directed by Savitri.
After said good bye to 18 years of acting career, Roja Ramani entered into Dubbing field in 1983. She has given dubbing to more than 400 films in a span of 20 years. She has given her voice to female lead in almost all the films. She stopped dubbing after given the voice to Tabu for 'Chennakesava Reddy'. But when M.S. Raju, the producer, asked her to give voice to Geeta in 'Nuvvostanante Nenoddantana', she couldn't hesitate. That was her last film as dubbing artiste.
Because of turned to an actress in childhood, there was no necessity of chance to study. When she was acting in 'Bhakta Prahlada', the AVM people arranged tuitions to her for education. She studied privately like that.
Very sorrowful moment of her was death of Kue, the pet dog. It's a Sail Burner, the Russian Breed.
She have a actor son Tarun and a daughter.